Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway

There is an urgent need for therapeutic development to combat infections caused by Rift Valley fever virus (RVFV), which causes devastating disease in both humans and animals. In an effort to repurpose drugs for RVFV treatment, our previous studies screened a library of FDA-approved drugs. The most...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Brahms, Ashwini, Mudhasani, Rajini, Pinkham, Chelsea, Kota, Krishna, Nasar, Farooq, Zamani, Rouzbeh, Bavari, Sina, Kehn-Hall, Kylene
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Structure and Assembly
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640838/
https://ncbi.nlm.nih.gov/pubmed/28794043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00968-17
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