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Sorafenib Impedes Rift Valley Fever Virus Egress by Inhibiting Valosin-Containing Protein Function in the Cellular Secretory Pathway

There is an urgent need for therapeutic development to combat infections caused by Rift Valley fever virus (RVFV), which causes devastating disease in both humans and animals. In an effort to repurpose drugs for RVFV treatment, our previous studies screened a library of FDA-approved drugs. The most...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Brahms, Ashwini, Mudhasani, Rajini, Pinkham, Chelsea, Kota, Krishna, Nasar, Farooq, Zamani, Rouzbeh, Bavari, Sina, Kehn-Hall, Kylene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640838/
https://ncbi.nlm.nih.gov/pubmed/28794043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00968-17
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