Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis

Despite over 60 years of research on antiviral drugs, very few are FDA approved to treat acute viral infections. Rift Valley fever virus (RVFV), an arthropod borne virus that causes hemorrhagic fever in severe cases, currently lacks effective treatments. Existing as obligate intracellular parasites,...

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Udgivet i:Antiviral Res
Main Authors: Bell, Todd M., Espina, Virginia, Senina, Svetlana, Woodson, Caitlin, Brahms, Ashwini, Carey, Brian, Lin, Shih-Chao, Lundberg, Lindsay, Pinkham, Chelsea, Baer, Alan, Mueller, Claudius, Chlipala, Elizabeth A., Sharman, Faye, de la Fuente, Cynthia, Liotta, Lance, Kehn-Hall, Kylene
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530372/
https://ncbi.nlm.nih.gov/pubmed/28442428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.04.011
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