High Content Image-Based Screening of a Protease Inhibitor Library Reveals Compounds Broadly Active against Rift Valley Fever Virus and Other Highly Pathogenic RNA Viruses

High content image-based screening was developed as an approach to test a protease inhibitor small molecule library for antiviral activity against Rift Valley fever virus (RVFV) and to determine their mechanism of action. RVFV is the causative agent of severe disease of humans and animals throughout...

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Bibliografiset tiedot
Päätekijät: Mudhasani, Rajini, Kota, Krishna P., Retterer, Cary, Tran, Julie P., Whitehouse, Chris A., Bavari, Sina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140764/
https://ncbi.nlm.nih.gov/pubmed/25144302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003095
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