Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells

In this study, we explore the regulatory roles of pro-inflammatory cytokine tumor necrosis factor alpha (TNF) in the innate immunity of macrophages against B. abortus infection. We show that infection of macrophage with B. abortus induces marked expression and secretion of TNF which subsequently bin...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Hop, Huynh T., Reyes, Alisha W. B., Huy, Tran X. N., Arayan, Lauren T., Min, WonGi, Lee, Hu J., Rhee, Man H., Chang, Hong H., Kim, Suk
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640714/
https://ncbi.nlm.nih.gov/pubmed/29062811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00437
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