Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells

In this study, we explore the regulatory roles of pro-inflammatory cytokine tumor necrosis factor alpha (TNF) in the innate immunity of macrophages against B. abortus infection. We show that infection of macrophage with B. abortus induces marked expression and secretion of TNF which subsequently bin...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Hop, Huynh T., Reyes, Alisha W. B., Huy, Tran X. N., Arayan, Lauren T., Min, WonGi, Lee, Hu J., Rhee, Man H., Chang, Hong H., Kim, Suk
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640714/
https://ncbi.nlm.nih.gov/pubmed/29062811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00437
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