Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells

In this study, we explore the regulatory roles of pro-inflammatory cytokine tumor necrosis factor alpha (TNF) in the innate immunity of macrophages against B. abortus infection. We show that infection of macrophage with B. abortus induces marked expression and secretion of TNF which subsequently bin...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Hop, Huynh T., Reyes, Alisha W. B., Huy, Tran X. N., Arayan, Lauren T., Min, WonGi, Lee, Hu J., Rhee, Man H., Chang, Hong H., Kim, Suk
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640714/
https://ncbi.nlm.nih.gov/pubmed/29062811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00437
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