Interleukin 10 suppresses lysosome-mediated killing of Brucella abortus in cultured macrophages

Brucella abortus is a Gram-negative zoonotic pathogen for which there is no 100% effective vaccine. Phagosomes in B. abortus–infected cells fail to mature, allowing the pathogen to survive and proliferate. Interleukin 10 (IL10) promotes B. abortus persistence in macrophages by mechanisms that are no...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Hop, Huynh Tan, Reyes, Alisha Wehdnesday Bernardo, Huy, Tran Xuan Ngoc, Arayan, Lauren Togonon, Min, WonGi, Lee, Hu Jang, Rhee, Man Hee, Chang, Hong Hee, Kim, Suk
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836127/
https://ncbi.nlm.nih.gov/pubmed/29301939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805556
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