Interleukin 10 suppresses lysosome-mediated killing of Brucella abortus in cultured macrophages

Brucella abortus is a Gram-negative zoonotic pathogen for which there is no 100% effective vaccine. Phagosomes in B. abortus–infected cells fail to mature, allowing the pathogen to survive and proliferate. Interleukin 10 (IL10) promotes B. abortus persistence in macrophages by mechanisms that are no...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Hop, Huynh Tan, Reyes, Alisha Wehdnesday Bernardo, Huy, Tran Xuan Ngoc, Arayan, Lauren Togonon, Min, WonGi, Lee, Hu Jang, Rhee, Man Hee, Chang, Hong Hee, Kim, Suk
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836127/
https://ncbi.nlm.nih.gov/pubmed/29301939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805556
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