Heat-stress-modulated induction of NF-κB leads to brucellacidal pro-inflammatory defense against Brucella abortus infection in murine macrophages and in a mouse model

BACKGROUND: Brucella causes a chronic and debilitating infection that leads to great economic losses and a public health burden. In this study, we demonstrated the brucellacidal effect of heat shock mediated by the induction of pro-inflammatory cytokines, reactive oxygen species (ROS) accumulation a...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Hop, Huynh Tan, Arayan, Lauren Togonon, Reyes, Alisha Wehdnesday Bernardo, Huy, Tran Xuan Ngoc, Min, Won Gi, Lee, Hu Jang, Rhee, Man Hee, Chang, Hong Hee, Kim, Suk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970535/
https://ncbi.nlm.nih.gov/pubmed/29801438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-018-1185-9
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