Caricamento...
Structure‐Guided Design of Peptides as Tools to Probe the Protein–Protein Interaction between Cullin‐2 and Elongin BC Substrate Adaptor in Cullin RING E3 Ubiquitin Ligases
Cullin RING E3 ubiquitin ligases (CRLs) are large dynamic multi‐subunit complexes that control the fate of many proteins in cells. CRLs are attractive drug targets for the development of small‐molecule inhibitors and chemical inducers of protein degradation. Herein we describe a structure‐guided bio...
Salvato in:
| Pubblicato in: | ChemMedChem |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5639367/ https://ncbi.nlm.nih.gov/pubmed/28776949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700359 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|