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Structure‐Guided Design of Peptides as Tools to Probe the Protein–Protein Interaction between Cullin‐2 and Elongin BC Substrate Adaptor in Cullin RING E3 Ubiquitin Ligases
Cullin RING E3 ubiquitin ligases (CRLs) are large dynamic multi‐subunit complexes that control the fate of many proteins in cells. CRLs are attractive drug targets for the development of small‐molecule inhibitors and chemical inducers of protein degradation. Herein we describe a structure‐guided bio...
Gorde:
| Argitaratua izan da: | ChemMedChem |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5639367/ https://ncbi.nlm.nih.gov/pubmed/28776949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700359 |
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