Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation

Pluripotent cells emanate from the inner cell mass (ICM) of the blastocyst and when cultivated under optimal conditions immortalize as embryonic stem cells (ESCs). The fundamental mechanism underlying ESC derivation has, however, remained elusive. Recently, we have devised a highly efficient approac...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Totonchi, Mehdi, Hassani, Seyedeh-Nafiseh, Sharifi-Zarchi, Ali, Tapia, Natalia, Adachi, Kenjiro, Arand, Julia, Greber, Boris, Sabour, Davood, Araúzo-Bravo, Marcos J., Walter, Jörn, Pakzad, Mohammad, Gourabi, Hamid, Schöler, Hans R., Baharvand, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639184/
https://ncbi.nlm.nih.gov/pubmed/28919260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.006
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