Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy

KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated malignancies. Cytotoxic drugs used for the the...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Granato, Marisa, Romeo, Maria Anele, Tiano, Mariangela Sara, Santarelli, Roberta, Gonnella, Roberta, Gilardini Montani, Maria Saveria, Faggioni, Alberto, Cirone, Mara
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638868/
https://ncbi.nlm.nih.gov/pubmed/29026157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13533-7
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