Carregant...
Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library
We constructed a large naïve human Fab library (3 × 10(10) colonies) from the lymphocytes of 809 human donors, assessed available diversities of the heavy-chain variable (VH) and κ light-chain variable (VK) domain repertoires, and validated the library by selecting Fabs against 10 therapeutically re...
Guardat en:
| Publicat a: | Mol Cells |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Korean Society for Molecular and Cellular Biology
2017
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638773/ https://ncbi.nlm.nih.gov/pubmed/28927259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.0106 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|