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Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression

We have previously demonstrated that mice expressing human complement receptor type 2 (CR2/CD21) during the CD43(+)/CD25(-) late pro-B cell stage of B cell development have marked changes in their subsequent B cell ontogeny. Here, we show that the humoral immune response to the T cell dependent anti...

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Detalhes bibliográficos
Publicado no:Immunobiology
Main Authors: Pappworth, Isabel Y., Hayes, Christine, Dimmick, Jason, Morgan, B. Paul, Holers, V. Michael, Marchbank, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638010/
https://ncbi.nlm.nih.gov/pubmed/21783272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2011.06.001
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