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RadH: A Versatile Halogenase for Integration into Synthetic Pathways
Flavin‐dependent halogenases are useful enzymes for providing halogenated molecules with improved biological activity, or intermediates for synthetic derivatization. We demonstrate how the fungal halogenase RadH can be used to regioselectively halogenate a range of bioactive aromatic scaffolds. Site...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5637929/ https://ncbi.nlm.nih.gov/pubmed/28722773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201706342 |
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