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Parkinson's Disease Is Not Simply a Prion Disorder

The notion that prion-like spreading of misfolded α-synuclein (α-SYN) causes Parkinson's disease (PD) has received a great deal of attention. Although attractive in its simplicity, the hypothesis is difficult to reconcile with postmortem analysis of human brains and connectome-mapping studies....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Surmeier, D. James, Obeso, José A., Halliday, Glenda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637112/
https://ncbi.nlm.nih.gov/pubmed/29021297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1787-16.2017
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