Blocking autophagy enhances the apoptotic effect of 18β-glycyrrhetinic acid on human sarcoma cells via endoplasmic reticulum stress and JNK activation

Sarcoma, a rare form of cancer, is unlike the much more common carcinomas as it occurs in a distinct type of tissue. The potent antitumor effects of 18β-glycyrrhetinic acid (GA), a novel naturally derived agent, have been demonstrated in various cancers. However, the effect of GA on human sarcoma, a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shen, Shuying, Zhou, Menglu, Huang, Kangmao, Wu, Yizheng, Ma, Yan, Wang, Jiying, Ma, Jianjun, Fan, Shunwu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636985/
https://ncbi.nlm.nih.gov/pubmed/28933787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.441
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