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Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response()
Excessive production of unsaturated aldehydes from oxidized lipoproteins and membrane lipids is a characteristic feature of cardiovascular disease. Our previous studies show that unsaturated lipid peroxidation-derived aldehydes such as 4-hydroxy-trans-2-nonenal (HNE) promote autophagy in rat aortic...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757667/ https://ncbi.nlm.nih.gov/pubmed/24024137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2012.10.003 |
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