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CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer

CDP138, a CDK5 binding partner, regulates cell proliferation and migration. However, the mechanisms by which CDP138 functions in these processes remain unclear. In this study, we show that CDP138 is frequently overexpressed and that high levels of CDP138 are correlated with lymph node metastasis in...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Lu, Yanwei, Ma, Jia, Li, Yan, Huang, Jing, Zhang, Sheng, Yin, Zhongyuan, Ren, Jinghua, Huang, Kai, Wu, Gang, Yang, Kunyu, Xu, Shuangbing
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636979/
https://ncbi.nlm.nih.gov/pubmed/28880265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.434
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