CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer

CDP138, a CDK5 binding partner, regulates cell proliferation and migration. However, the mechanisms by which CDP138 functions in these processes remain unclear. In this study, we show that CDP138 is frequently overexpressed and that high levels of CDP138 are correlated with lymph node metastasis in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lu, Yanwei, Ma, Jia, Li, Yan, Huang, Jing, Zhang, Sheng, Yin, Zhongyuan, Ren, Jinghua, Huang, Kai, Wu, Gang, Yang, Kunyu, Xu, Shuangbing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636979/
https://ncbi.nlm.nih.gov/pubmed/28880265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.434
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