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High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center
High-fidelity DNA replication depends on a proofreading 3′–5′ exonuclease that is associated with the replicative DNA polymerase. The replicative DNA polymerase DnaE1 from the major pathogen Mycobacterium tuberculosis (Mtb) uses its intrinsic PHP-exonuclease that is distinct from the canonical DEDD...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636811/ https://ncbi.nlm.nih.gov/pubmed/29021523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00886-w |
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