Scope & Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin

We have systematically explored three approaches based on Fmoc chemistry SPPS for the total chemical synthesis of the key depsipeptide intermediate for the efficient total chemical synthesis of insulin. The approaches used were: stepwise Fmoc chemistry SPPS; the ‘hybrid method’, in which maximally-p...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Chemistry
Autors principals: Dhayalan, Balamurugan, Mandal, Kalyaneswar, Rege, Nischay, Weiss, Michael A., Eitel, Simon H., Meier, Thomas, Schoenleber, Ralph O., Kent, Stephen B.H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636692/
https://ncbi.nlm.nih.gov/pubmed/27905149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605578
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars