Nalaganje...
Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking
The slow delayed-rectifier potassium current (I(Ks)) is crucial for human cardiac action potential repolarization. The formation of I(Ks) requires co-assembly of the KCNQ1 α-subunit and KCNE1 β-subunit, and mutations in either of these subunits can lead to hereditary long QT syndrome types 1 and 5,...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636153/ https://ncbi.nlm.nih.gov/pubmed/29020060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186293 |
| Oznake: |
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