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Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS

CD14(+)CD16(+) monocytes transmigrate into the CNS of HIV-positive people in response to chemokines elevated in the brains of infected individuals, including CXCL12. Entry of these cells leads to viral reservoirs, neuroinflammation, and neuronal damage. These may eventually lead to HIV-associated ne...

詳細記述

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書誌詳細
出版年:J Leukoc Biol
主要な著者: Veenstra, Mike, Williams, Dionna W., Calderon, Tina M., Anastos, Kathryn, Morgello, Susan, Berman, Joan W.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Leukocyte Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636044/
https://ncbi.nlm.nih.gov/pubmed/28754798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0517-167R
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