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Frontline Science: CXCR7 mediates CD14(+)CD16(+) monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS

CD14(+)CD16(+) monocytes transmigrate into the CNS of HIV-positive people in response to chemokines elevated in the brains of infected individuals, including CXCL12. Entry of these cells leads to viral reservoirs, neuroinflammation, and neuronal damage. These may eventually lead to HIV-associated ne...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Veenstra, Mike, Williams, Dionna W., Calderon, Tina M., Anastos, Kathryn, Morgello, Susan, Berman, Joan W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636044/
https://ncbi.nlm.nih.gov/pubmed/28754798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0517-167R
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