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JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14(+)CD16(+) monocytes in HIV-infected individuals

Monocyte transmigration across the BBB is a critical step in the development of cognitive deficits termed HAND that affect 40–70% of HIV-infected individuals, even with successful antiretroviral therapy. The monocyte subsets that enter the CNS during HIV infection are not fully characterized. We exa...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Williams, Dionna W., Anastos, Kathryn, Morgello, Susan, Berman, Joan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304417/
https://ncbi.nlm.nih.gov/pubmed/25420915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.5A0714-347R
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