Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14(+)CD16(+) Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

As HIV infected individuals live longer, the prevalence of HIV associated neurocognitive disorders is increasing, despite successful antiretroviral therapy. CD14(+)CD16(+) monocytes are critical to the neuropathogenesis of HIV as they promote viral seeding of the brain and establish neuroinflammatio...

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Detalhes bibliográficos
Main Authors: Williams, Dionna W., Calderon, Tina M., Lopez, Lillie, Carvallo-Torres, Loreto, Gaskill, Peter J., Eugenin, Eliseo A., Morgello, Susan, Berman, Joan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724935/
https://ncbi.nlm.nih.gov/pubmed/23922698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069270
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