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Fatty acid synthase regulates the pathogenicity of Th17 cells

T cell activation and effector function is characterized by changes in metabolism. Altered metabolism is common to almost all types of activated T cells, but fatty acid synthesis seems to especially drive the formation of Th17 cells. Indeed, research has demonstrated that inhibition of early fatty a...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Young, Kathryne E., Flaherty, Stephanie, Woodman, Kaitlyn M., Sharma-Walia, Neelam, Reynolds, Joseph M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636042/
https://ncbi.nlm.nih.gov/pubmed/28848043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3AB0417-159RR
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