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Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration

Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular programming underlying Th17 cell pathogenicity remains insufficiently understood. Activation of Toll-like receptor 2 (TLR2) increases Th17 cell inflammatory potential, but little is known regarding the mechanistic outc...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Marks, Kathryne E., Flaherty, Stephanie, Patterson, Kristen M., Stratton, Matthew, Martinez, Gustavo J., Reynolds, Joseph M.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270556/
https://ncbi.nlm.nih.gov/pubmed/34192530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109303
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