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Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis
Skeletal metastases, the leading cause of death in advanced breast cancer patients, depend on tumor cell interactions with the mineralized bone extracellular matrix. Bone mineral is largely composed of hydroxyapatite (HA) nanocrystals with physicochemical properties that vary significantly by anatom...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5635895/ https://ncbi.nlm.nih.gov/pubmed/28923958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708161114 |
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