Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B* 35:02 as a risk factor

BACKGROUND & AIMS: Minocycline hepatotoxicity can present with prominent autoimmune features in previously healthy individuals. The aim of this study was to identify genetic determinants of minocycline DILI in a well-phenotyped cohort of patients. METHODS: Caucasian patients with minocycline DIL...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Urban, Thomas Jacob, Nicoletti, Paola, Chalasani, Naga, Serrano, Jose, Stolz, Andrew, Daly, Ann K., Aithal, Guruprasad P., Dillon, John, Navarro, Victor, Odin, Joseph, Barnhart, Huiman, Ostrov, David, Long, Nanye, Cirulli, Elizabeth Theresa, Watkins, Paul Brent, Fontana, Robert John
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634615/
https://ncbi.nlm.nih.gov/pubmed/28323125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2017.03.010
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