Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B* 35:02 as a risk factor

BACKGROUND & AIMS: Minocycline hepatotoxicity can present with prominent autoimmune features in previously healthy individuals. The aim of this study was to identify genetic determinants of minocycline DILI in a well-phenotyped cohort of patients. METHODS: Caucasian patients with minocycline DIL...

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Publicat a:J Hepatol
Autors principals: Urban, Thomas Jacob, Nicoletti, Paola, Chalasani, Naga, Serrano, Jose, Stolz, Andrew, Daly, Ann K., Aithal, Guruprasad P., Dillon, John, Navarro, Victor, Odin, Joseph, Barnhart, Huiman, Ostrov, David, Long, Nanye, Cirulli, Elizabeth Theresa, Watkins, Paul Brent, Fontana, Robert John
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634615/
https://ncbi.nlm.nih.gov/pubmed/28323125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2017.03.010
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