The Spectrum of Statin Hepatotoxicity: Experience of the Drug Induced Liver Injury Network

BACKGROUND AND AIMS: The HMG-CoA reductase inhibitors (statins) are widely prescribed for patients with hyperlipidemia and are generally well tolerated. Mild elevations in serum aminotransferases arise in up to 3% of treated patients, but clinically apparent drug induced liver injury is rare. The ai...

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Hlavní autoři: Russo, Mark W., Hoofnagle, Jay H., Gu, Jiezhun, Fontana, Robert J, Barnhart, Huiman, Kleiner, David E, Chalasani, Naga, Bonkovsky, Herbert L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110177/
https://ncbi.nlm.nih.gov/pubmed/24700436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27157
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