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Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder, affecting millions of people worldwide. Although dysfunction of multiple neurotransmitter systems including cholinergic, glutamatergic and GABAergic systems has been associated with AD progression the und...

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Publicado en:Mol Neurodegener
Autores principales: Wang, Yue, Wu, Zheng, Bai, Yu-Ting, Wu, Gang-Yi, Chen, Gong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633901/
https://ncbi.nlm.nih.gov/pubmed/29017573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0213-9
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