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Defining the current scope and limitations of dual noncanonical amino acid mutagenesis in mammalian cells
The ability to site-specifically incorporate two distinct noncanonical amino acids (ncAAs) into the proteome of a mammalian cell with high fidelity and efficiency will have many enabling applications. It would require the use of two different engineered aminoacyl-tRNA synthetase (aaRS)/tRNA pairs, e...
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| Udgivet i: | Chem Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5633785/ https://ncbi.nlm.nih.gov/pubmed/29081953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02560b |
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