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Therapeutic T cell engineering

Genetically engineered T cells are powerful new medicines, offering hope for curative responses in patients with cancer. Chimaeric antigen receptors (CARs) are a class of synthetic receptors that reprogram lymphocyte specificity and function. CARs targeting CD19 have demonstrated remarkable potency...

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Detalles Bibliográficos
Publicado en:Nature
Autores principales: Sadelain, Michel, Rivière, Isabelle, Riddell, Stanley
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632949/
https://ncbi.nlm.nih.gov/pubmed/28541315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22395
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