Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors

The role of Notch signaling in human innate lymphoid cell (ILC) differentiation is unclear, although IL-7 and IL-15 promote differentiation of natural cytotoxicity receptor (NCR) NKp44(+) group 3 ILCs (NCR(+)ILC3s) and conventional NK (cNK) cells from CD34(+) hematopoietic progenitor cells (HPCs) ex...

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Foilsithe in:J Immunol
Main Authors: Kyoizumi, Seishi, Kubo, Yoshiko, Kajimura, Junko, Yoshida, Kengo, Hayashi, Tomonori, Nakachi, Kei, Moore, Malcolm A., van den Brink, Marcel R. M., Kusunoki, Yoichiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: AAI 2017
Ábhair:
Immune System Development
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632839/
https://ncbi.nlm.nih.gov/pubmed/28893953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601711
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