Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors

The role of Notch signaling in human innate lymphoid cell (ILC) differentiation is unclear, although IL-7 and IL-15 promote differentiation of natural cytotoxicity receptor (NCR) NKp44(+) group 3 ILCs (NCR(+)ILC3s) and conventional NK (cNK) cells from CD34(+) hematopoietic progenitor cells (HPCs) ex...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kyoizumi, Seishi, Kubo, Yoshiko, Kajimura, Junko, Yoshida, Kengo, Hayashi, Tomonori, Nakachi, Kei, Moore, Malcolm A., van den Brink, Marcel R. M., Kusunoki, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Immune System Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632839/
https://ncbi.nlm.nih.gov/pubmed/28893953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601711
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