Age-associated changes in the differentiation potentials of human circulating hematopoietic progenitors to T- or NK-lineage cells

Age-associated changes of T- and NK-cell (T/NK) potential of human hematopoietic stem cells are unknown. Here, we enumerate and characterize T/NK precursors among CD34-positive/lineage marker-negative (CD34(+)Lin(−)) cell populations circulating in normal human adult peripheral blood (PB) by a limit...

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Detalhes bibliográficos
Main Authors: Kyoizumi, Seishi, Kubo, Yoshiko, Kajimura, Junko, Yoshida, Kengo, Imai, Kazue, Hayashi, Tomonori, Nakachi, Kei, Young, Lauren F., Moore, Malcolm A., van den Brink, Marcel R.M., Kusunoki, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679208/
https://ncbi.nlm.nih.gov/pubmed/23670190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203189
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