Meclizine Prevents Ovariectomy-Induced Bone Loss and Inhibits Osteoclastogenesis Partially by Upregulating PXR

Pregnane X receptor (PXR) which belongs to the nuclear hormone receptor superfamily plays vital roles in several biological functions, especially in the inflammatory procedure. Besides that, PXR is revealed by recent studies to have essential effects on bone tissue. As an agonist of PXR, meclizine i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Pharmacol
मुख्य लेखकों: Guo, Jiachao, Li, Weijin, Wu, Yingxing, Jing, Xingzhi, Huang, Junming, Zhang, Jiaming, Xiang, Wei, Ren, Ranyue, Lv, Zhengtao, Xiao, Jun, Guo, Fengjing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2017
विषय:
Pharmacology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632684/
https://ncbi.nlm.nih.gov/pubmed/29046637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00693
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