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Modular Approach to pseudo-Neoclerodanes as Designer Kappa Opioid Ligands
Informed by previous semisynthetic work on salvinorin A, a modular total synthesis has been developed capable of producing novel compounds targeting the kappa opioid receptor. The strategy has permitted the deliberate simplification and introduction of functionality about the target molecule to prov...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5632227/ https://ncbi.nlm.nih.gov/pubmed/28910112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b02684 |
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