LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma

DNA damaging chemotherapy and radiation are widely used standard-of-care modalities for the treatment of cancer. Nevertheless, the outcome for many patients remains poor and this may be attributed, at least in part, to highly effective DNA repair mechanisms. Ataxia-telangiectasia mutated and Rad3-re...

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Publicado en:J Pharm Biomed Anal
Autores principales: Kiesel, Brian F., Scemama, Jonas, Parise, Robert A., Villaruz, Liza, Iffland, Andre, Doyle, Austin, Ivy, Percy, Chu, Edward, Bakkenist, Christopher J., Beumer, Jan H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632222/
https://ncbi.nlm.nih.gov/pubmed/28888173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2017.08.037
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