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Mechanisms of Flucytosine Resistance in Cryptococcus gattii May Be Independent of the FCY2-FCY1-FUR1 Pathway

BACKGROUND: Cryptococcosis is an opportunistic fungal infection caused by both Cryptococcus neoformans and its sibling species, Cryptococcus gattii. Flucytosine (5FC) is one of the most widely used antifungals against Cryptococcus spp., yet very few studies have looked at the molecular mechanisms re...

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Publicado en:Open Forum Infect Dis
Autores principales: Vu, Kiem, Thompson, George R, Roe, Chandler, Sykes, Jane, Dreibe, Elizabeth, Lockhart, Shawn, Meyer, Wieland, Engelthaler, David M, Gelli, Angie
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.134
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