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Mechanisms of Flucytosine Resistance in Cryptococcus gattii May Be Independent of the FCY2-FCY1-FUR1 Pathway

BACKGROUND: Cryptococcosis is an opportunistic fungal infection caused by both Cryptococcus neoformans and its sibling species, Cryptococcus gattii. Flucytosine (5FC) is one of the most widely used antifungals against Cryptococcus spp., yet very few studies have looked at the molecular mechanisms re...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Vu, Kiem, Thompson, George R, Roe, Chandler, Sykes, Jane, Dreibe, Elizabeth, Lockhart, Shawn, Meyer, Wieland, Engelthaler, David M, Gelli, Angie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.134
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