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Fluconazole Susceptibility in Cryptococcus gattii Is Dependent on the ABC Transporter Pdr11
Cryptococcus gattii isolates from the Pacific Northwest have exhibited higher fluconazole MICs than isolates from other sites. The mechanism of fluconazole resistance in C. gattii is unknown. We sought to determine the role of the efflux pumps Mdr1 and Pdr11 in fluconazole susceptibility. Using biol...
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| izdano v: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775963/ https://ncbi.nlm.nih.gov/pubmed/26643330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01777-15 |
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