Galidesivir, a Direct-Acting Antiviral Drug, Abrogates Viremia in Rhesus Macaques Challenged with Zika Virus

BACKGROUND: Zika virus (ZIKV) was first isolated from a sentinel rhesus monkey in 1947. ZIKV infection in humans is associated with serious neurological and reproductive complications. No antiviral or protective vaccine is yet available. Galidesivir an adenosine analog is a potent viral RNA-dependen...

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Publicat a:Open Forum Infect Dis
Autors principals: Lim, So-Yon, Osuna, Christa, Lakritz, Jessica, Chen, Elsa, Yoon, Gyeol, Taylor, Ray, MacLennan, Steve, Leonard, Michael, Giuliano, Enzo, Mathis, Amanda, Berger, Elliot, Babu, Ys, Sheridan, William, Whitney, James
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631744/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx162.129
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