Depletion of CD4(+) T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques

CD4(+) T cells play a central role in the immunopathogenesis of HIV/AIDS, and their depletion during chronic HIV infection is a hallmark of disease progression. However, the relative contribution of CD4(+) T cells as mediators of antiviral immune responses and targets for virus replication is still...

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Detalhes bibliográficos
Main Authors: Ortiz, Alexandra M., Klatt, Nichole R., Li, Bing, Yi, Yanjie, Tabb, Brian, Hao, Xing Pei, Sternberg, Lawrence, Lawson, Benton, Carnathan, Paul M., Cramer, Elizabeth M., Engram, Jessica C., Little, Dawn M., Ryzhova, Elena, Gonzalez-Scarano, Francisco, Paiardini, Mirko, Ansari, Aftab A., Ratcliffe, Sarah, Else, James G., Brenchley, Jason M., Collman, Ronald G., Estes, Jacob D., Derdeyn, Cynthia A., Silvestri, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204830/
https://ncbi.nlm.nih.gov/pubmed/22005304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46023
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