A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques

Zika virus infection in humans has been associated with serious reproductive and neurological complications. At present, no protective antiviral drug treatment is available. Here, we describe the testing and evaluation of the antiviral drug, galidesivir, against Zika virus infection in rhesus macaqu...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Lim, So-Yon, Osuna, Christa E., Best, Katharine, Taylor, Ray, Chen, Elsa, Yoon, Gyeol, Kublin, Jessica L., Schalk, Dane, Schultz-Darken, Nancy, Capuano, Saverio, Safronetz, David, Luo, Ma, MacLennan, Steve, Mathis, Amanda, Babu, Yarlagadda S., Sheridan, William P., Perelson, Alan S., Whitney, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370316/
https://ncbi.nlm.nih.gov/pubmed/32522808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau9135
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