A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques

Zika virus infection in humans has been associated with serious reproductive and neurological complications. At present, no protective antiviral drug treatment is available. Here, we describe the testing and evaluation of the antiviral drug, galidesivir, against Zika virus infection in rhesus macaqu...

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Publicat a:Sci Transl Med
Autors principals: Lim, So-Yon, Osuna, Christa E., Best, Katharine, Taylor, Ray, Chen, Elsa, Yoon, Gyeol, Kublin, Jessica L., Schalk, Dane, Schultz-Darken, Nancy, Capuano, Saverio, Safronetz, David, Luo, Ma, MacLennan, Steve, Mathis, Amanda, Babu, Yarlagadda S., Sheridan, William P., Perelson, Alan S., Whitney, James B.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370316/
https://ncbi.nlm.nih.gov/pubmed/32522808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau9135
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