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Induced Human Intestinal Organoids (iHIOs) as Model Systems for Chemotherapy-associated Clostridium difficile (CD) Infections

BACKGROUND: Patients undergoing cytotoxic chemotherapy are ten times more likely to develop Clostridium difficile infections (CDI) than the general patient population. Efforts to outline pathophysiologic mechanisms underlying this disproportionate incidence have been limited by the lack of disease-r...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Apewokin, Senu, Pradhan, Suman, Frerick, Michael, Weiss, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631062/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.946
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