ZTI-01 Treatment Improves Survival of Animals Infected with Multidrug Resistant Pseudomonas aeruginosa

BACKGROUND: ZTI-01 (fosfomycin, FOS, for injection) is currently under US development to treat complicated urinary tract infections. ZTI-01 is unique compared with other antimicrobials in that it inhibits an early step in cell wall synthesis via covalent binding to MurA. ZTI-01 demonstrates broad in...

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Publicat a:Open Forum Infect Dis
Autors principals: Lawrenz, Matthew B, denDekker, Ashley Eb, Cramer, Daniel E, Gabbard, Jon D, Lafoe, Kathryn M, Pfeffer, Tia L, Sotsky, Julie B, Vanover, Carol D, Ellis-Grosse, Evelyn J, Warawa, Jonathan M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631034/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1213
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